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HYDROLASE. Crystal structure of the dihydroorotase ... DE NOVO PYRIMIDINE BIOSYNTHESIS, AMIDOHYDROLASE SUPERFAMILY, METALLOENZYME, ZINC BINDING, HISTIDINATE ANION ...
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HYDROLASE. Crystal structure of the dihydroorotase domain of human CAD E1637T mutant bound to substrate at pH 6.0; HYDROLASE, DE NOVO PYRIMIDINE BIOSYNTHESIS ...
HYDROLASE / DE NOVO PYRIMIDINE BIOSYNTHESIS / AMIDOHYDROLASE SUPERFAMILY / METALLOENZYME / ZINC BINDING / HISTIDINATE ANION · Function and homology information.
Dihydroorotate dehydrogenase (DHODH) is an enzyme of the de novo pyrimidine synthesis pathway that provides nucleotides for RNA/DNA synthesis essential for ...
HEADER HYDROLASE 18-SEP-13 4C6N TITLE CRYSTAL ... NOVO PYRIMIDINE BIOSYNTHESIS, AMIDOHYDROLASE KEYWDS 2 SUPERFAMILY, METALLOENZYME, ZINC BINDING, HISTIDINATE ...
We find that seemingly redundant enzymes thymidine kinase and cytidine deaminase are required, not for their typical role in salvaging exogenous precursors, but ...
Protein Leading De Novo Pyrimidine Biosynthesis. Structure, 2017. 25(6): p. 912-+. 55. Lee, M., et al., Kinetic and Structural Analysis of Mutant ...
Jul 19, 2021 · The pathway for de novo pyrimidine synthesis is essential for cell proliferation and is conserved in all living organisms, but the covalent ...
to family 1A are dimeric proteins ... flavin-dependent reductases: pyridine nucleotide-binding and interac- ... de novo pyrimidine biosynthesis in Trypanosoma cruzi ...
... Hydrolase within the Amidohydrolase Superfamily ... Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine ... The bacterial de novo pyrimidine ...